News

New funding available to boost beta cell research in the UK

December 20, 2024
Beta cells illustration

We’re launching a new funding call to address the limited availability of stem cell-derived beta cells for research purposes.  

The aim is to facilitate more high-quality research into beta cell therapies, speeding up progress towards a cure for type 1 diabetes. 

To achieve this, we’ve partnered with the Advanced Regenerative Manufacturing Institute (ARMI), the US leading organisation in manufacturing cells, tissues and organs. 

Funding is available for UK-based researchers to test if stem cell-derived beta cells produced by ARMI can survive shipment from the US to the UK. And if they can, whether they work as expected in both lab studies and living organisms.   

We’re inviting UK experts with a track record of producing and testing stem cell-derived beta cells to apply for funding to test ARMI’s beta cells. Funding is available for up to three sites across the UK.  

Successful researchers will also have the opportunity to directly compare ARMI’s beta cells with their own lab-made beta cells. This may help them to improve their own production process and identify the most effective product for wider rollout. 

The hope is that it will enable the development of a reliable supply of high-quality, pre-made stem cell-derived beta cells for use by UK scientists. By saving researchers time and ensuring consistency across studies, this initiative is expected to accelerate the development of new beta cell replacement therapies. 

Apply for funding

Details about the call can be found here. You’ll need to submit your application by 31 January 2025. 

If you’re interested in applying, we strongly encourage you to attend our funding call webinar on 8 January 2025 at 14:00 GMT and reach out to the T1DGC Research Funding Team to discuss the opportunity further (smfgrandchallenge@diabetes.org.uk) 

The Advanced Regenerative Manufacturing Institute (ARMI | BioFabUSA) said:

“ARMI is proud to partner with the Type 1 Diabetes Grand Challenge to advance beta cell research. By providing high-quality, stem cell-derived beta cells for validation, we aim to accelerate breakthroughs in type 1 diabetes treatment and improve the scalability of regenerative therapies. This initiative represents a critical step in bridging global efforts to bring innovative solutions to patients.”

Professor Matthias Hebrok, Vice Chair of the Type 1 Diabetes Grand Challenge Scientific Advisory Panel, said:  

Testing stem cell derived islets produced by a foundry for their functional properties upon being sent to the UK is critical to ensure high quality tissues will be available to accelerate research in type 1 diabetes.”